![]() If the acrosome reaction is not functioning in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI), in which the sperm is injected in the egg may be necessary, whereas intrauterine injection (IUI) in which the sperm is placed within the cervix, will not be effective. Additionally, it can predict the level of intervention required during assisted reproductive treatments. This test of sperm function can explain infertility in the cases of normal semen analysis when no female infertility factors are present. The results of this test indicate the quality of the sperm’s acrosome. The acrosome reaction test uses a trigger, such as hormones or certain electrolytes to trigger the acrosome reaction sequence in a lab and evaluates the sperm’s performance. While a standard sperm analysis can visually test the sperm for the presence of a typical acrosome, it cannot test the acrosome’s ability to function normally when introduced to an egg. There are several tests that evaluate sperm.
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